Director, Chemical Development

We are seeking a highly skilled and motivated Director with expertise in small molecule process development and manufacturing to join our CMC team. In this role, you will lead the technical development strategy for small molecule drug substances from IND-enabling studies through late-stage development and commercial readiness for assigned programs.

What You Will Do

Provide technical leadership, mentorship, and people leadership for internal scientists, while building organizational capability within Chemical Development and effectively leading CDMO partners. Lead process R&D activities at CDMO partners and provide technical oversight for scale-up and tech transfer from the laboratory to the pilot plant and, as appropriate, to commercial manufacturing.

Why It Might Be a Fit

This role offers an exciting opportunity to contribute to the advancement of Cytokinetics’ growing portfolio of novel therapeutics. You will have the opportunity to lead complex cross-functional initiatives, influence senior stakeholders, and represent the function effectively in high-level forums.

Requirements

• Ph.D. in chemistry with 12+ years of pharmaceutical/biotech industry experience in small molecule drug substance development; or M.S. with 15+ years of relevant experience
• Strong expertise in synthetic organic chemistry and experience in process development, scale-up, and GMP manufacturing support for drug substances
• Strong understanding of the solid-state properties of small molecules
• Direct, hands-on experience leading CDMOs and ensuring high-quality execution and delivery
• Well-versed with cGMP regulations and quality systems relevant to pharmaceutical development and manufacturing
• Demonstrated ability to lead complex cross-functional initiatives, influence senior stakeholders, and represent the function effectively in high-level forums

Benefits

• Competitive salary
• Equity
• Healthcare
• PTO
• Retirement
• Learning budget
• Parental leave
• Wellness
• Remote flexibility
• Stipends
• Bonus/commission
• Paid holidays