Manufacturing Bioprocess Associate (Downstream)

The Manufacturing Bioprocess Associate (Downstream) performs complex biologics manufacturing activities with minimal supervision. This role supports upstream or downstream operations including buffer/media preparation, process equipment operation, system setup, and sterilization support. The role is part of a 24/7 manufacturing operation and requires flexibility to work irregular hours, including nights and weekends. The position involves working in environments with extreme temperatures, high noise levels, restricted laboratory access, and exposure to dust, gas, fumes, steam, or chemicals.

What You Will Do

Execute upstream (seed train, bioreactor) or downstream (chromatography, TFF) unit operations in accordance with batch requirements. Prepare and test media or buffer solutions following SOPs and batch instructions, including pH and conductivity adjustments. Operate and maintain glass wash and autoclave systems to ensure proper sterilization and availability of process components.

Why It Might Be a Fit

The ideal candidate will have 2–4 years of biologics manufacturing experience, working knowledge of GMP documentation, cleanroom behavior, and aseptic techniques, and experience with new facility startup, equipment commissioning/qualification. The role demands good eye/hand coordination, visual acuity, and proficiency in using keyboards, computers, and phones. Sensory awareness—including the ability to detect and distinguish smells and sounds—is important for safety and quality assurance.

Requirements

• Associate or Bachelor degree in a science related field or equivalent relevant experience
• 2–4 years of biologics manufacturing experience (upstream or downstream)
• Working knowledge of GMP documentation, cleanroom behavior, and aseptic techniques
• Experience with new facility startup, equipment commissioning/qualification
• Deep understanding of upstream (cell culture/fermentation) and Downstream (purification) unit operations for biologics manufacturing
• Prior experience supporting client-sponsored manufacturing or operating in a CDMO environment

Benefits

• Competitive salary
• Benefits package
• Paid time off
• Health insurance
• Retirement plan
• Learning budget
• Parental leave
• Wellness programs
• Visa/relocation assistance
• Remote flexibility
• Bonus/commission
• Paid holidays