Role OverviewWe are hiring an ML Engineer, Discovery Applications to build the high level, end-to-end scientific workflows that power real bench to bench decision making inside the Mithrl platform. This role focuses on building the application layer on top of the AI Co-Scientist. Your work will shape how scientists discover biomarkers, identify and validate targets, design experiments, and run early discovery programs that extend all the way to IND-enabling work.
What You Will Do
Build full discovery applications that support biomarker identification, target discovery, target validation, small molecule design workflows, and gene therapy programs. Stand up new analyses that support application logic and improve or extend the existing analysis suite.
Why It Might Be a Fit
You will design multi step workflows that combine analysis modules, ML models, domain logic, and agentic reasoning into complete applications. These applications cover biomarker discovery, target ID, target validation, small molecule hit identification and optimization, and gene therapy workflows.
Requirements
- Strong experience in ML, computational biology, scientific computing, or a related field
- Deep understanding of the drug discovery and preclinical development cycle including early discovery, target identification, target validation, hit identification, hit to lead, lead optimization, and IND-enabling work
- Experience building analytical workflows or application logic for biological or scientific data
- Familiarity with key discovery analysis methods such as differential expression, pathway analysis, clustering, enrichment, and target scoring
- Proficiency in Python and scientific computing libraries and comfort with building multi step workflows
- Ability to convert scientific questions into structured, reproducible workflows that support real decision making
- Strong communication skills and ability to collaborate with cross functional engineering and biology teams
Benefits
- Comprehensive PPO health coverage through Anthem (medical, dental, and vision)
- 401(k) with top-tier plans
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