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Principal Scientist, Computational Protein Design
Flagship Pioneering
Cambridge, MA
Category
Research
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Job Description
Flagship Pioneering is seeking a Principal Scientist – Computational Protein Design to lead technical development on computational antibody design. This role will involve AI-based design methods, optimizing antibody developability, and applying those methods to advance novel medicines. The successful candidate will work within a matrixed, cross-functional environment and collaborate with Pioneering Medicines and Flagship's scientific platforms.
Requirements
PhD in Biochemistry, Structural Biology, Biophysics, Protein Engineering, Computational Biology, Computer Science, or related field
5+ years of relevant industry experience
Proven experience in end-to-end antibody design and optimization
Strong track record in AI and computational methods
Experience analyzing and interpreting antibody developability data
Experience leading projects in antibody discovery or biologics development
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