Scientist II, Antibody Engineering

Manifold Bio
Boston, MA
Category Research
Job Description
Manifold Bio is a biotech company focused on targeted biologics using a novel in vivo-centric discovery approach. They are seeking an exceptional Associate Scientist to contribute to the generation of high-quality AAV lots for rodent and non-human-primate (NHP) studies. The role involves scale-up of AAV production, rigorous purification, quality control, and collaboration with internal and external partners.

Requirements

  • B.S. or M.S. in Biochemistry, Molecular Biology, Chemical Engineering, Virology, or a related field
  • 2–5 years of relevant industry experience
  • Hands-on experience producing AAV in HEK293 and/or baculovirus-Sf9 systems
  • Proficiency with downstream purification techniques
  • Experience with PCR, qPCR, ELISA, A260/280, and CGE
  • Experience with bioreactor operation and process automation
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