Senior Research Associate or Scientist 1 (Polytope Bio)

Astera Institute
Any Location, CA
Category Research
Job Description
Role Overview

Join our experimental biology team to build and operate a high-throughput experimental platform at the heart of Polytope Bio. Design and execute experiments focused on high-throughput cloning and strain engineering, develop and optimize workflows for DNA assembly, library construction, and screening assays, analyze experimental data, and work closely with computational researchers to translate biological measurements into high-quality datasets.

What You Will Do

Design and execute experiments, develop and optimize assays, own research projects, analyze and interpret data, build experimental infrastructure, and maintain laboratory equipment and workflows.

Why It Might Be a Fit

This is an opportunity to work at the intersection of experimental biology and frontier AI in a highly collaborative, fast-moving research environment. Your work will help shape the technical direction of a new research platform from the ground up.

Requirements

  • Bachelor's or Master's degree in molecular biology, biochemistry, bioengineering, or a related field
  • significant hands-on research experience, including at least 3 years of industry experience
  • hands-on experience engineering yeast or other microbes, including strain construction, genetic engineering, and characterization of strains
  • strong hands-on experience with molecular biology techniques, including primer design, Golden Gate cloning, DNA assembly, plasmid construction, and library generation
  • ability to take an experimental question from a loosely defined objective through experimental design, execution, analysis, and iteration
  • resourcefulness and persistence when experiments do not work as expected
  • ability to work effectively with both experimental biologists and computational/AI researchers and communicate scientific results clearly

Benefits

  • base salary of $90,000 to $120,000
  • potential for a founding research role in a future spinout
  • authorship of high-impact open-source datasets, methods, and models
  • full benefits package including health insurance, a company-sponsored retirement plan, vision, dental, daily lunch, and more
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